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Video instructions and help with filling out and completing cms clinical lab fee schedule 2020-2021
Explain it Music Music then we have assumed we can't give you that listen you have to let's just see Wow okay we're gonna start back up before we do just so you know it was discussed here prior to lunch once the presenters have have talked we will start right up with the panel meeting so it'll be a continuation so stick around our next speaker is Ben row from myriad genetic laboratories good afternoon my name is Ben row and I'm the laboratory director at Mary genetic labs thank you for the opportunity to talk about our Polaris test for prostate cancer aggressiveness so just briefly on the slide the current state of prostate cancer lists the statistics in terms of newly diagnosed cases the growth in the reporting of cases of prostate cancer and the annual spend suffice it to say that there's quite a bit of spending is currently the third ranked by in terms of cancer treatment and there is widespread concern potential over treatment due to screening programs and this brings us to this brings us to our code eight 1x4 one which describes myriads laboratory tests for prostate cancer called pro lares this is used to more precisely stratify patients by directly measuring tumor biology and this best is for men with a biopsy confirmed diagnosis of prostate cancer to determine aggressiveness as you can see from the code descriptor for polaris eight 1x4 one is a prostate ma analyzing RNA expression levels by rt-pcr or reverse transcription followed by quantitative real-time pcr there are any expression levels being analyzed are from a set of 46 genes 31 of which are considered content genes involved in cell cycle progression and the other 15 are housekeeping genes an algorithm is applied to generate a prole era score which has been proven in multiple published studies to be a predictor of prostate cancer outcomes this unique patient specific information is independent of standard clinical pathologic features such as PSA and Gleason score and the personalized information in the test report is used by the patient and physician to make more precise treatment choices based on the patient's ten-year risk of dying from prostate cancer when an individual is diagnosed with localized prostate cancer he is unclassified into an American neurological Association risk category but regardless of the risk category most men will seek intervention in the form of surgery radiation or a combination of both the high rate of intervention occurs despite the high risk of treatment related complications and the fact that the vast majority of prostate cancers do not cause death even when initial management is conservative we believe that this high intervention rate is because risk stratification using typical prognostic factors continues to leave physicians and patients with uncertainty about the aggressiveness of prostate cancer in turn this results in under utilization of active surveillance and increased costs to the health care system using the Polaris tests however enhances the existing.